SCIOL Genetic Science is an open access journal publishes papers on latest developments related to human and animal genome, specific gene expressions in health and disease.

We consider publishing original research articles, reviews, reports, commentaries, editorials, proceedings, letters to the editor, methodologies and technologies. The journal publishes genetic studies of organisms ranging from microbes to humans.

The journal provides immediate access to the published content under the open access policy. This journal operates a single blind review process. The articles will be examined by editorial board members, Inhouse and external review team and published every in HTML/Web version and PDF formats.

    Articles


  • Letter to the Editor  | April 20, 2018 

    Inbreeding Depression and Heterosis: Explanation by Two-Component Genome Composition

    Boris F Chadov

    Citation: Chadov BF (2018) Inbreeding Depression and Heterosis: Explanation by Two-Component Genome Composition. SCIOL Genet Sci 2018;1:41-44.

     

    Abstract: Inbreeding in animals and plants leads to the formation of weak and low-fertile offspring (inbreeding depression). The reverse phenomenon, i.e. the formation of strong and high-fertile offspring, superior to their parents (heterosis), occurs when crossing representatives of a species distant by kinship.

    Research Article  | April 19, 2018 

    Lipoplex Delivery System for P11 Gene: A Risk Based Quality by Design Approach

    Manit Gandhi, Ambikanandan Misra and Rajashree Mashru

    Citation: Gandhi M, Misra A, Mashru R (2018) Lipoplex Delivery System for P11 Gene: A Risk Based Quality by Design Approach. SCIOL Genet Sci 2018;1:22-40.

     

    Abstract: The purpose of this study was to explore Quality by Design (QbD) principle for the preparation of lipoplex containing p11 cDNA to prove both feasibility and convenience of executing QbD concept to liposome based gene delivery system. Product and process indulgence will assist in decreasing the inconsistency of critical material and process parameters, which provide quality in productivity and diminish the risk.

    Research Article  | October 14, 2017 

    The Genetics of Conditional Mutations and Individual Developmental Programs in D. melanogaster

    BF Chadov, EV Chadova and NB Fedorova

    Citation: Chadov BF, Chadova EV, Fedorova NB (2017) The Genetics of Conditional Mutations and Individual Developmental Programs in D. Melanogaster. SCIOL Genet Sci 2017;1:3-21.

     

    Abstract: A new class of mutations referred to as conditional mutations was discovered in Drosophila melanogaster. These mutations cause death in a restrictive genotype but survival and reproduction are promoted in a permissive genotype.

    Letter to the Editor  | October 09, 2017 

    Congenital Genetic Hemoglobin Disorder and the Resistance to Tropical Blood Infection: An Important Phenomenon in Indochina

    Somsri Wiwanitkit and Viroj Wiwanitkit

    Citation: Wiwanitkit S, Wiwanitkit V (2017) Congenital Genetic Hemoglobin Disorder and the Resistance to Tropical Blood Infection: An Important Phenomenon in Indochina. SCIOL Genet Sci 2017;1:1-2.

     

    Abstract: Dear Editor, the congenital hemoglobin disorder is a common group of genetic disorder seen worldwide. In tropical Asia, it is also an important cause of tropical anemia.